Personal Genomics in Primary Care

Research Type: 
Genomics and Primary Care


Our group is completing a National Institutes of Health (NIH) funded U34 planning grant on “Educational, Behavioral, or Social Studies for Translation of Genetic Factors in Common Diseases.” Dr. Roberts leads a multidisciplinary team, including Dr. Mack Ruffin from Family Medicine, with expertise in physician education, clinical trials in primary care, health services research and patient-provider communication. Along with funded centers at Mount Sinai Hospital, North Shore-Long Island Jewish Health System, and Fox Chase Cancer Center we will submit a grant application to NIH in July to conduct a randomized clinical trial across multiple sites, including our partners at Henry Ford Health System in Detroit.

Study Aims

The trial would test the 1) efficacy of a tailored, web-based skills training program teaching primary care providers how to interpret and communicate genomic risk information; and 2) psychological and behavioral effects of providing patients with personalized genomic risk information for five common diseases (colon cancer, diabetes, heart disease, osteoporosis, and prostate cancer). Findings will assist efforts to improve the genomic literacy of both patients and primary care providers such that genetic testing is used appropriately to inform screening recommendations, motivate positive patient behavior changes, and facilitate referral to specialty providers.

Key Personnel

J. Scott Roberts, Ph.D., Principal Investigator 

Mack T. Ruffin IV.,M.D.,M.P.H., Co-Investigator

Gwen L. Alexander, Ph.D., Co-Investigator (Henry Ford Health System)

Stewart C. Alexander, Ph.D., Co-Investigator (Duke University)

Jamie Myles, Ph.D., Data Coordinator